Hypertension is a major cause of concern not just in the elderly but also in the youngsters an effort was made to formulate a fast dissolving film containing telmisartan which is used in the treatment of hypertension with a view to improve the onset of action, therapeutic efficacy, patient compliance and convenience the major. Orally fast dissolving films (ofdfs) have been introduced in the market recently as they provide convenience and ease of use over orally fast dissolving film is the type of drug delivery system which when master thesis in “formulation and evaluation of fast dissolving film of an antimigraine drug. Abstract in the recent years, many of the pharmaceutical groups are focusing their research on rapid dissolving technology amongst the plethora of avenues explored for rapid drug releasing product, fast dissolving films technology is gaining much attention fast dissolving films evolved over the past few years from the. In addition to active pharmaceutical ingredient (api), major components of os are film forming polymer and plasticizer, which impart desired shape and elasticity to oral strip (os) since fast disintegrating technology relies on the use of hygroscopic excipients it is generally liable for moisture uptake. Introduction fast dissolving films for oral administration was a novel approach, for the patients who experience difficulties in swallowing tablets or capsules geriatric, pediatric and dysphasic patients associated with many medical conditions face a problem of difficulty in swallowing the solid dosage forms.
Title: formulation and characterization of acetaminophen nanoparticles in orally disintegrating films authors: ai-nemrawi, nusaiba k affiliation: aa(long island university, the brooklyn center) publication: proquest dissertations and theses thesis (phd)--long island university, the brooklyn center, 2015. A thesis presented to the faculty of pharmacy university of santo tomas in partial fulfillment of the requirements for the degree bachelor of science in pharmacy abstract this study focused on the formulation of an orally fast- dissolving film using diphenhydramine hcl as the model drug by solvent. Fast-dissolving drug-delivery systems were first developed in the late 1970s as an alternative to conventional tablet, capsule and syrups these are used in the form of fast dissolving tablet (fdts) and fast dissolving oral films (fdofs) these disintegrate and dissolve within a minute, without needing water. Development and analytical characterization inaugural-dissertation b oromucosal film preparations: classification and characterization methods 35 c formulation development of the use of fast-dissolving orodispersible films will circumvent the challenge of correct use as mentioned in the guideline: simple.
Preparation and characterization of fast-dissolving oral films for pediatric use inaugural-dissertation zur erlangung des doktorgrades der mathematisch-naturwissenschaftlichen fakultät der heinrich-heine-universität düsseldorf vorgelegt von verena ingeborg garsuch aus leipzig düsseldorf. Fast dissolving oral film (fdof) is used as a novel approach, as it dissolve rapidly in mouth and directly reaches to the systemic circulation oral film technology fulfills all the requirements of potential solid dosage form the aim of this study is to formulate and evaluate the (fdof) of an anticholinergic drug ( dicyclomine) and.
The fast dissolving drug delivery system consists of a very thin strip that is just placed on the patient's tongue or any oral mucosal tissue, instantly wet by secretion the film rapidly hydrates and adheres onto the location it then quickly disintegrates and dissolves to release the drug for oromucosal and intragastric absorption. Rizatriptan benzoate, a serotonin 5-ht1 receptor agonist is a new generation antimigraine drug which has oral bioavailability of 47% due to hepatic first pass metabolism the present study investigated the possibility of developing rizatriptan benzoate fast dissolving sublingual films allowing fast, reproducible drug. This review article overview the advancement in the oral dosage forms, application, formulation consideration, method of preparation, evaluation, marketed product and patented technologies of oral fast disintegrating films key words: fast dissolving film low dose high solubility high permeability patient compliance.